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The over-the-counter (OTC) version of Nexium is available in 20-milligram (mg) capsules.

Prilosec, with omeprazole as its active ingredient, was the first heartburn drug introduced and is now available over the counter.

The recommended dose of Nexium is 20 milligrams once daily for patients with acid reflux disease.

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Doctors prescribe this proton pump inhibitor to relieve chronic heartburn associated with gastroesophageal reflux disease, and to promote healing of erosive esophagitis, or damage to the esophagus caused by stomach acid washing upward.

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Surgical Options Fundoplication is the standard surgical treatment for GERD.

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Once the esophagus has healed, Nexium may also be used to prevent the return of erosive esophagitis.

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India's Ranbaxy Laboratories originally boasted first-to-file, 180-day exclusivity on the drug, whose patent expired in May.

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